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A1c Blood Test
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What is the A1c (hemoglobin A1c, Hb1c, HbA1c or HgA1c) test, and what is its significance?

In the normal 120-day life span of the red blood cell, glucose molecules join hemoglobin, forming glycated hemoglobin. Once a hemoglobin molecule is glycated, it remains that way. A buildup of glycated hemoglobin within the red cell reflects the average level of glucose to which the cell has been exposed during its life cycle. We measure the amount of this glycated hemoglobin with the A1c test.

Hemoglobin is found inside red blood cells. Its job is to carry oxygen from the lungs to all the cells of the body. Hemoglobin, like all proteins, links up with sugars such as glucose.

People with diabetes have too much sugar in their bloodstream. This extra glucose enters the red blood cells and links up (or glycates) with molecules of hemoglobin. The more excess glucose in the blood, the more hemoglobin gets glycated. It is possible to measure the percentage of glycated glucose in the blood. The result is an overview of the average blood glucose control for the past few months, and is the A1c number.

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